Are there atypical presentations of SARS-CoV-2 infection with non-respiratory symptoms?

Yes, this virus seems to be a true chameleon. While patients usually experience respiratory symptoms, atypical presentations have indeed been observed and described in the current literature. This may be due to the fact that the ACE-2, the target receptor for the SARS-CoV-2 virus is ubiquitously found in the human body.

Presumably about 48% of patients present with primary gastrointestinal symptoms such as abdominal pain, vomiting and/or diarrhea, as described in a study from Wuhan. In some cases gastrointestinal symptoms were present with no concomittant respiratory symptoms at all.